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Preparation and Cytotoxicity of Poly(Methyl Methacrylate) Nanoparticles for Drug Encapsulation

✍ Scribed by Mendes, Anderson N.; Hubber, Isabela; Siqueira, Mônica; Barbosa, Gleyce Moreno; de Lima Moreira, Davyson; Holandino, Carla; Pinto, José Carlos; Nele, Marcio

Book ID
121235826
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
158 KB
Volume
319
Category
Article
ISSN
1022-1360

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Poly(methyl malate) Nanoparticles: Forma
Poly(methyl malate) Nanoparticles: Formation, Degradation, and Encapsulation of Anticancer Drugs
✍ Alberto Lanz-Landázuri; Montserrat García-Alvarez; José Portilla-Arias; Antxon M 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 593 KB

## Abstract PMLA nanoparticles with diameters of 150–250 nm are prepared, and their hydrolytic degradation is studied under physiological conditions. Degradation occurs by hydrolysis of the side chain methyl ester followed by cleavage of the main‐chain ester group with methanol and L‐malic acid as