Preparation and characterization of polyvinyl alcohol based biomaterials: Water sorption and in vitro blood compatibility study

✍ Scribed by Shefali Mishra; R. Bajpai; R. Katare; A. K. Bajpai

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 246 KB
• Volume: 100
• Category: Article
• ISSN: 0021-8995
• DOI: 10.1002/app.23177

✦ Synopsis

Abstract

Semi‐interpenetrating polymer networks (semi‐IPNs) based on polyvinyl alcohol (PVA) and crosslinked polyacrylamide (PAM) were prepared by redox polymerization and further characterized by FTIR, ESEM, and XRD techniques. The semi‐IPNs of varying compositions were investigated for their water sorption behavior, and the network parameters like average molecular weight between crosslinks (M~C~) and crosslink density were evaluated from water imbibition measurements. The semi‐IPNs were also judged for their in vitro blood compatibility by blood clot formation and percent hemolysis test. It was noticed that the chemical architecture exert a profound effect on the over all performance of the biomaterials. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 2402–2408, 2006