Preparation and characterization of metal-thiosteroid complexes

✍ Scribed by G. Pouskouleli; P. Kourounakis; T. Theophanides

• Book ID: 104138232
• Publisher: Elsevier Science
• Year: 1976
• Tongue: English
• Weight: 236 KB
• Volume: 18
• Category: Article
• ISSN: 0020-1693
• DOI: 10.1016/s0020-1693(00)95576-2

✦ Synopsis

The complexes SNL-Hg-OAc and SXZ-Hg-OAc, where SNLCOCH, = Spironolactone or 7a-thioacetyl-17-hydroxy-3-oxo-androstene-17a-propionic acid ylactone, SXZCOCH3 = Spiroxazone or 7a-thioacetyl-(17R)-spiro[androst-4-enl7,2(3 H)furan] and OAc = acetate have been prepared by the reaction between the mercuric salt (CH,COO),Hg

and the thiosteroid by stirring at room temperature in absolute ethanol solution. Infrared, proton nuclear magnetic and analytical data are reported for the complexes and the thiosteroids.