Preparation and characterization of insulin nanoparticles using chitosan and Arabic gum with ionic gelation method

✍ Scribed by Mohammad Reza Avadi; Assal Mir Mohammad Sadeghi; Nasser Mohammadpour; Saideh Abedin; Fatemeh Atyabi; Rassoul Dinarvand; Morteza Rafiee-Tehrani

• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 442 KB
• Volume: 6
• Category: Article
• ISSN: 1549-9634
• DOI: 10.1016/j.nano.2009.04.007

✦ Synopsis

From the clinical editor:

This paper summarizes the development of a nanoparticulate system based on ionic gelation between chitosan and gum arabic for oral delivery of insulin. if preclinical studies in animal models will indicate reliable and quantifiable delivery of insulin, this method may pave the way to a novel and less invasive way of administering insulin to diabetes patients.