Preparation and characterization of chitosan microparticles intended for controlled drug delivery
โ Scribed by J.A Ko; H.J Park; S.J Hwang; J.B Park; J.S Lee
- Book ID
- 108454174
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 494 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0378-5173
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The production and modification of chitosan microparticles using crosslinking agents and papain were evaluated for controlled release applications. Chitosan microparticles were produced and crosslinked with sodium tripolyphosphate (TPP) 10% (w/v) solution or glutaraldehyde (GLU) 0.75% (w/w), with su
## Abstract In this article we describe our preliminary work involving the use of depolymerized, low molecular weight chitosan nanoparticles as carriers for proteins and peptides. We hypothesized that the molecular weight of chitosan could favorably modulate the particle and protein release charact