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Preparation and Characterization of Biodegradable and Electroactive Polymer Blend Materials Based on mPEG/Tetraaniline and PLLA

✍ Scribed by Yadong Liu; Jun Hu; Xiuli Zhuang; Peibiao Zhang; Xuesi Chen; Yen Wei; Xianhong Wang

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
546 KB
Volume
11
Category
Article
ISSN
1616-5187

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✦ Synopsis

Abstract

A novel PGTA diblock copolymer containing electroactive TEA and mPEG is described. Biodegradable PLLA/PGTA polymer blends are shown to be electroactive. Nanopores of different sizes can be formed on the surface of the polymer blends. An MTT assay shows that the PLLA/PGTA blends exhibited reduced cytotoxicity as compared to TEA due to the introduction of the biocompatible PLLA moiety. Cell culture results show that the cells grow better when they were adhered to the surface of the PLLA/PGTA blends. The 80/20 wt.‐% PLLA/PGTA blend shows the best biocompatibility and an electroactivity that accelerates the differentiation of rat C6 glioma cells. magnified image

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