Preparation and characterization of a multi-cylinder microelectrode coupled with a conventional glassy carbon electrode and its application to the detection of dopamine

✍ Scribed by Wenfeng Peng; Erkang Wang

• Publisher: Elsevier Science
• Year: 1993
• Tongue: English
• Weight: 802 KB
• Volume: 281
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(93)85028-i

✦ Synopsis

A multi-cylinder microekctrode coupled with a conventional glassy carbon disc electrode (MCM/GC) was prepared and characterized using cyclic vokammetry and chronoamperometry. It was demonstrated that in the same way as one observed a steady-state current at closely spaced microelectrodes when redox recycling takes place, the same effect can be obtained with the MCM/GC device. The experimental results obtained with KsFefCN), solutions were compared with a previously developed theory. Further, it was demonstrated that with a carbon fibre MCM/GC device, the voltammetric behaviour of dopamine is greatly improved by virtue of redox recycling, hence giving high sensitivity. The steady-state collection current was linearly related to dopamine concentration in the range 1 X 10e4 to 5 X 10e7 mol l-l, and the detection limit was 2 X lo-' mol 1-r. The influence of coexisting ascorbic acid was also investigated. This device was applied successfully in the determination of dopamine hydrochloride in pharmaceutical preparations.