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Preparation and characterization of a cocrystalline suspension of [LysB28,ProB29]-human insulin analogue

✍ Scribed by Michael R. DeFelippis; Diane L. Bakaysa; Maureen A. Bell; Mark A. Heady; Shun Li; Susan Pye; Karen M. Youngman; Jerry Radziuk; Bruce H. Frank


Book ID
109388919
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
118 KB
Volume
87
Category
Article
ISSN
0022-3549

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✍ Alice Ciencialová; Lenka Žáková; Jiří Jiráček; Jana Barthová; Tomislav Barth 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB

## Abstract The preparation and characterization of two novel LysB29 selectively labelled fluorescent derivatives of human insulin are described. Two probes were chosen: 4‐chloro‐7‐nitrobenz‐2‐oxa‐1,3‐diazole (NBD) and 7‐methoxycoumarin‐4‐acetic acid (MCA), which have a relatively small, compact st