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Preparation and characteristics of interleukin-6-dependent hybridoma

✍ Scribed by E. N. Klyushnenkova; V. V. Malaitsev


Book ID
104945957
Publisher
Springer US
Year
1992
Tongue
English
Weight
366 KB
Volume
114
Category
Article
ISSN
0007-4888

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Sp2/0 hybridoma cells die principally by apoptosis in batch culture. We have found that cultures of the Sp2/0 hybridoma exhibit increased viability in response to interleukin 6 (IL-6) supplementation relative to control cultures during serum shiftdown experiments. When shifted from a medium containi