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Preparation and characteristic of lactose-oleoylchitosan and the application of its self-aggregates as drug delivery system

✍ Scribed by Shanshan Zhang; Yanyan Li; Guodong Ren; Xiguang Chen; Xiangjun Meng


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
486 KB
Volume
121
Category
Article
ISSN
0021-8995

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✍ Heinz Nau; Rainer Zierer πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 603 KB

## Abstract Human therapeutic valproic acid (VPA) levels could be maintained in the mouse for a period of 1 week by constant rate application via subcutaneously implanted osmotic minipumps. Also, the concentrations of VPA metabolites observed in mouse plasma were similar to those seen in human plas