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Preparation and Characterisation of Hydrophobically Modified Hydroxypropylcellulose: Side-Chain Crystallisation

✍ Scribed by Delia López-Velázquez; Antonio Bello; Ernesto Pérez


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
177 KB
Volume
205
Category
Article
ISSN
1022-1352

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✦ Synopsis


Abstract

Summary: Hydroxypropylcellulose has been hydrophobically modified by reaction with different amounts of palmitoyl chloride. When the degree of substitution is sufficiently high, the side chains are able to produce lateral crystallisation, which has been analysed by DSC and diffraction experiments, using both conventional and synchrotron radiation. The melting temperatures and enthalpies depend on the degree of substitution, in such a way that it is relatively easy to get melting temperatures close to that of the human body, although a rather wide melting region is obtained.

X‐ray diffractograms of the original HPC sample and of the modified specimens.

magnified imageX‐ray diffractograms of the original HPC sample and of the modified specimens.