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Preparation and characterisation of attenuated cold-adapted influenza A reassortants derived from the A/Leningrad/134/17/57 donor strain

✍ Scribed by M.D Wareing; G.A Marsh; G.A Tannock

Book ID: 117430840
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 196 KB
Volume: 20
Category: Article
ISSN: 0264-410X
DOI: 10.1016/s0264-410x(02)00056-7

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## Abstract The immunogenicity of the Russian cold‐adapted (ca) donor stains, A/Leningrad (Len)/134/17/57 and A/Leningrad/134/47/57, and the US strain A/Ann Arbor (AA)/6/60‐ca, were compared in BALB/c mice with their respective wild‐type parental viruses. Each ca donor strain was less immunogenic t