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Preparation and application of a chiral C3-building block for amino alcohol synthesis by bakers' yeast reduction of 1-acyloxy-3-azido-2-propanone

✍ Scribed by Toshio Sato; Toshihiro Mizutani; Yoshiyuki Okumura; Tamotsu Fujisawa


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
120 KB
Volume
30
Category
Article
ISSN
0040-4039

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The preparative separation of the enantiomers of the title compound, a versatile chiral building block for the synthesis of unnatural amino acid esters, by high performance liquid chromatography on a chiral stationary phase (CSP), is reported for the first time. The CSP consists of amylose-(3,5-dime