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Preparation and Absolute Configuration of Some Iris Essential Oil Constituents of the 5-methylsafranic-acid series

✍ Scribed by Christian Chapuis; Karl H. Schulte-Elte


Publisher
John Wiley and Sons
Year
1995
Tongue
German
Weight
833 KB
Volume
78
Category
Article
ISSN
0018-019X

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✦ Synopsis


Ca. 18000 US%/kg of absolute oil. We are indebted to Prof. J. Garner0 and D . Joulain for a copy of this analysis. This is an energetically unfavorable (uphill) transformation. Indeed, 13c is totally converted into 16c under basic conditions (MeONa, MeOH, 0.1 mol-equiv., 2 5 O ; 90%). For a comparison of the thermodynamic stability of 13c and 16c, calculated by semi-empirical method PM3 (negative values in kcal/mol f2.0, MOPAC 6.0 QCPE), see [3], and for stereoisomer comparison, based on MM2 calculations (positive values in KJ/mol, MACROMODEL 4.0), see [4]. Thus, tram-8a: 103.4,