## BACKGROUND. Plasma transforming growth factor-1 (TGF1) levels are increased in many malignancies at the time of diagnosis, including all forms of lung carcinoma. Therefore, the potential use of TGF1 as a plasma marker to predict the long term outcome of lung carcinoma patients treated with r
Preoperative plasma levels of transforming growth factor β1 strongly predict clinical outcome in patients with bladder carcinoma
✍ Scribed by Shahrokh F. Shariat; Ja-Hong Kim; Ben Andrews; Michael W. Kattan; Thomas M. Wheeler; Isaac Y. Kim; Seth P. Lerner; Kevin M. Slawin
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 93 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0008-543X
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Nasopharyngeal carcinomas (NPCs) of non-keratinizing type are strongly associated with Epstein-Barr virus (EBV). EBV and its gene products induce the synthesis and/or release of transforming growth factor 1 (TGF-1) from human cells and platelets. TGF-1 is an immunosuppressive cytokine, and many t
## Background: Transforming growth factor-beta1 (tgf-beta1) acts as a potent inhibitor of cell growth and tumor progression but loss of this negative regulation can contribute to tumor development. some studies have reported an association between disease progression and tgf-beta1 expression in pat