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Preoperative imaging of colorectal cancers. Targeting the epithelial membrane antigen with a radiation-labeled monoclonal antibody

✍ Scribed by Brian R. Davidson; Helen Young; Wendy A. Waddington; John Babich; Gill A. Clarke; Mike D. Short; Paul B. Boulos; Jenny Styles; Christopher Dean; Peter J. Ell


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
682 KB
Volume
69
Category
Article
ISSN
0008-543X

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✍ Håkan Mellstedt; Jan-Erik Frodin; Peter Biberfeld; Jan Fagerberg; Ricardo Gisomb 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 751 KB

## Abstract The anti‐tumor effector functions of unconjugated MAb in cancer therapy are not fully understood. Direct cytotoxic mechanisms have been demonstrated as well as induction of anti‐idiotypic (ab~2~) and anti‐anti‐idiotypic (ab~3~) antibodies. If such a humoral response is induced, then an