Prenatal ultrasound diagnosis of Beckwith–Wiedemann syndrome
✍ Scribed by Yogesh G Shah; Leon Metlay
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 371 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0091-2751
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## Abstract Beckwith‐Wiedemann syndrome is an inherited disorder most commonly characterized by prenatal or postnatal overgrowth, macroglossia, omphalocele, unusual earlobe creases, and increased risk of neoplasia. Several reported cases of this syndrome have been prenatally diagnosed, but no repor
Wiedemann-Beckwith syndrome (WBS) is a heterogeneous overgrowth syndrome associated with malformations and an elevated risk of developing embryonal tumors. WBS is a multigenic disorder caused by dysregulation of imprinted growth regulatory genes within the 11p15 region. Elucidation of the genetic ca
We report a case of congenital pancreatic cyst detected prenatally by ultrasound in a fetus with evidence for a diagnosis of Beckwith-Wiedemann syndrome (BWS). Neonatal hypoglycaemia was prevented. The cyst was managed by internal drainage. This is the second reported case of BWS associated with pan