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Prenatal ultrasonographic findings of dominant polycystic kidney disease and postnatal renal evolution

✍ Scribed by Sinibaldi, D.; Malena, S.; Mingarelli, R.; Rizzoni, G.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
494 KB
Volume
65
Category
Article
ISSN
0148-7299

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✦ Synopsis


Autosomal dominant polycystic kidney disease (ADPKD) is a relatively common genetic disorder, and its prenatal diagnosis has been reported with increasing frequency. Nevertheless, no data are available on the significance of prenatal ultrasound (US) patterns in predicting postnatal renal function and outcome. We report on one case of ADPKD diagnosed prenatally by US, and on two cases diagnosed immediately after birth, with different prenatal US and renal outcomes. Data on prenatal US findings and postnatal renal evolution are scanty and largely incomplete. Apparently, none of the prenatal findings are consistently different in cases with and without normal postnatal renal function and blood pressure. More complete information on prenatal US findings and postnatal renal evolution is urgently needed.