Prenatal ultrasonographic appearance of “Cornelia de Lange” syndrome
✍ Scribed by Leo F. Drolshagen; Gudron Durmon; Mike Berumen; Deland D. Burks
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 609 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0091-2751
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## Abstract Cornelia de Lange syndrome (CdLS) is a multiple congenital anomaly/mental retardation syndrome consisting of characteristic dysmorphic features, microcephaly, hypertrichosis, upper limb defects, growth retardation, developmental delay, and a variety of associated malformations. We prese
## Abstract Observations about the natural history of aging in Cornelia de Lange syndrome (CdLS) are made, based on 49 patients from a multidisciplinary clinic for adolescents and adults. The mean age was 17 years. Although most patients remain small, obesity may develop. Gastroesophageal reflux pe
Chromosome studies were performed on 13 patients with the Cornelia de Lange syndrome. With the technique of chromosome banding analysis, no chromosomal abnormalities were found.