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Prenatal sonographic diagnosis of Pena-Shokeir syndrome type I, or fetal akinesia deformation sequence

✍ Scribed by Ohlsson, Arne ;Fong, Katherine W. ;Rose, Toby H. ;Moore, Donald C. ;Optiz, John M. ;Reynolds, James F.


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
453 KB
Volume
29
Category
Article
ISSN
0148-7299

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✦ Synopsis


We report on a familial case of Pena-Shokeir syndrome type I (fetal akinesia deformation sequence) born to healthy parents. The antenatal ultrasound diagnosis was based on hydramnios, restricted limb movements, decreased fetal chest movements, small chest, arthrogryposis, clubfoot, fixed extension of knees, fixed flexion of elbows, camptodactyly, kyphosis of thoracic spine, cryptorchidism, and small muscle bulk. Thymic hyperplasia was noted at autopsy.