Prenatal screening for Down's syndrome: some psychosocial implications of a ‘screening for all’ policy
✍ Scribed by LD Bryant; JM Green; J Hewison
- Book ID
- 119739492
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 49 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0033-3506
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We conducted a study to investigate ethnic group differences in levels of serum markers used in screening for Down's syndrome [serum alpha-fetoprotein (AFP), unconjugated oestriol (uE,), total human chorionic gonadotrophin (hCG), free a-and free P-hCG, and dimeric inhibin-A], to estimate the extent
The value of measuring inhibin-A (asA dimer) with human chorionic gonadotrophin (total or the sub-units free a-hCG and free P-hCG separately), alpha-fetoprotein (AFP), and unconjugated oestriol (uE,) was examined to determine the effect on the performance of serum screening for Down's syndrome betwe
Maternal serum screening for Down syndrome involves biochemical tests such as alpha-fetoprotein ( FP), human chorionic gonadotrophin (hCG) and unconjugated oestriol (uE 3 ), either alone or in combination, that have variable detection and false-positive rates. Choosing a screening protocol requires