Prenatal screening for Down syndrome: pre-analytical precautions
โ Scribed by C. Doche; M. Bartoli; S. Mercier; JP Demiaux; J. Gascht; B. Dingeon
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 45 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0197-3851
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๐ SIMILAR VOLUMES
Maternal serum screening for Down syndrome involves biochemical tests such as alpha-fetoprotein ( FP), human chorionic gonadotrophin (hCG) and unconjugated oestriol (uE 3 ), either alone or in combination, that have variable detection and false-positive rates. Choosing a screening protocol requires
In this study we report a new triple test that combines serum AFP, urine โค-core fragment of hCG, total urine estriol, and maternal age for calculating individual Down syndrome odds in the second trimester. The urine โค-core fragment/estriol ratio was used as a single screening variable. Analyte level