Prenatal screening for Down syndrome in England and Wales and population-based birth outcomes
โ Scribed by Rebecca Smith-Bindman; Philip Chu; Peter Bacchetti; Jonathan J Waters; David Mutton; Eva Alberman
- Book ID
- 114491135
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 126 KB
- Volume
- 189
- Category
- Article
- ISSN
- 1097-6868
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We aimed to determine how differences in the age at which women had their pregnancies influenced the expected detection and false-positive rates of serum screening for Down 's syndrome (i) between 1970 and 1993 in England and Wales, and (ii) between regions and districts of England and Wales in 1991
Maternal serum screening for Down syndrome involves biochemical tests such as alpha-fetoprotein ( FP), human chorionic gonadotrophin (hCG) and unconjugated oestriol (uE 3 ), either alone or in combination, that have variable detection and false-positive rates. Choosing a screening protocol requires