The Concept Of Prenatal Gene Therapy -- Candidate Diseases For Prenatal Gene Therapy -- Vector Systems For Prenatal Gene Therapy: Choosing Vectors For Different Applications -- Vector Systems For Prenatal Gene Therapy: Principles Of Adenovirus Design And Production -- Vector Systems For Prenatal Gene Therapy: Principles Of Retrovirus Vector Design And Production -- Vector Systems For Prenatal Gene Therapy: Principles Of Adeno-associated Virus Vector Design And Production -- Vector Systems For Prenatal Gene Therapy: Principles Of Non-viral Vector Design And Production -- Use Of Manipulated Stem Cells For Prenatal Therapy -- Animal Models For Prenatal Gene Therapy: Choosing The Right Model -- Animal Models For Prenatal Gene Therapy: Rodent Models For Prenatal Gene Therapy -- Animal Models For Prenatal Gene Therapy: The Sheep Model. Animal Models For Prenatal Gene Therapy: The Nonhuman Primate Model -- Choice Of Surrogate And Physiological Markers For Prenatal Gene Therapy -- Monitoring For Potential Adverse Effects Of Prenatal Gene Therapy: Use Of Large Animal Models With Relevance To Human Application -- Monitoring For Potential Adverse Effects Of Prenatal Gene Therapy: Mouse Models For Developmental Aberrations And Inadvertent Germ Line Transmission -- Monitoring For Potential Adverse Effects Of Prenatal Gene Therapy: Genotoxicity Analysis In Vitro And On Small Animal Models Ex Vivo And In Vivo -- Risks, Benefits And Ethical, Legal, And Societal Considerations For Translation Of Prenatal Gene Therapy To Human Application. Edited By Charles Coutelle, Simon N. Waddington. Includes Bibliographical References And Index.