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Prenatal exposure to morphine alters kinetic properties of NMDA receptor-mediated synaptic currents in the hippocampus of rat offspring

โœ Scribed by San Nan Yang; Jung-Mou Yang; Jian-Nan Wu; Yu-Hshun Kao; Wen-Ya Hsieh; Chih Chang Chao; Pao-Luh Tao

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
424 KB
Volume
10
Category
Article
ISSN
1050-9631

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Alteration of NMDA receptor-mediated syn
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Synaptic responses mediated by the N-methyl-D-aspartate receptor (NMDAr) and non-NMDAr activation were compared in CA1 hippocampal region of young (3-4 months old) and aged (25-33 months old) Sprague-Dawley rats with the use of ex vivo extracellular recordings techniques. In aged rats, the amplitude