Wolf-Hirschhorn Syndrome (WHS) is caused by distal deletion of the short arm of chromosome 4 and is characterized by growth deยฎciency, mental retardation, a distinctive, `greek-helmet' facial appearance, microcephaly, ear lobe anomalies, and sacral dimples. We report a family with a balanced chromos
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Prenatal diagnosis of Wolf-Hirschhorn syndrome (4p-) in association with congenital hypospadias and foot deformity
โ Scribed by Halil Aslan; Nilay Karaca; Seher Basaran; Hayri Ermis; Yavuz Ceylan
- Book ID
- 115009700
- Publisher
- BioMed Central
- Year
- 2003
- Tongue
- English
- Weight
- 374 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1471-2393
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## Abstract ## BACKGROUND WolfโHirschhorn syndrome (WHS) is a wellโknown genetic condition characterized by typical facial anomalies, midline defects, skeletal anomalies, prenatal and postnatal growth retardation, hypotonia, mental retardation, and seizures. Affected patients with a microdeletion
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