✦ LIBER ✦

Prenatal diagnosis of congenital heart disease

✍ Scribed by Ulrich Gembruch

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 143 KB
Volume: 17
Category: Article
ISSN: 0197-3851
DOI: 10.1002/(sici)1097-0223(199712)17:13<1283::aid-pd296>3.0.co;2-t

No coin nor oath required. For personal study only.

✦ Synopsis

Owing to the widely different levels of experience of examiners, there is a large discrepancy in study results of second trimester ultrasound screening for fetal malformations, which is a result of varying levels of obstetric scanning expertise prevalent at the reporting centre. This holds particularly true for the prenatal diagnosis of congenital heart disease where detection rates ranging from 0 per cent to 60 per cent are being reported. On the other hand, congenital heart disease affects about 4-8 per 1000 live births and is a leading cause of infant mortality, whereas prenatal diagnosis could possibly prevent death and long-term morbidity in some of these neonates. Various screening concepts for more effective detection of congenital heart diseases are analysed in this article, including the more recent technique of early echocardiography between 13 and 15 weeks of gestation. High-risk groups are defined and the group of fetuses with increased thickness of nuchal translucency seems to be of particular interest.

📜 SIMILAR VOLUMES

Evaluation of prenatal diagnosis of cong

Evaluation of prenatal diagnosis of congenital heart disease

✍ C. Stoll; Y. Alembik; B. Dott; M. J. Meyer; A. Pennerath; M. O. Peter; B. De Gee 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 2 views

Prenatal diagnosis performed by fetal ultrasound scan is now a routine part of antenatal care in many countries. That an increasing number of fetal anomalies may be detected on prenatal ultrasound is beyond doubt. What is possible is not, however, always practical, especially where congenital heart

PRENATAL DIAGNOSIS OF CONGENITAL VARICEL

PRENATAL DIAGNOSIS OF CONGENITAL VARICELLA INFECTION

✍ ALESSANDRA KUSTERMANN; CINZIA ZOPPINI; BEATRICE TASSIS; MARZIA DELLA MORTE; GIUS 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB 👁 2 views

Fourteen fetuses at risk of Varicella-Zoster virus (VZV) infection underwent prenatal diagnosis at 10-24 weeks' gestation by a combination of chorionic villus sampling, amniocentesis, and fetal blood sampling. Polymerase chain reaction (PCR) was done on fetal and placental tissues, using primers whi

Prenatal diagnosis of congenital adrenal

Prenatal diagnosis of congenital adrenal hyperplasia

✍ Marcus, E. S. ;Holcombe, J. H. ;Tulchinsky, D. ;Rich, R. R. ;Riccardi, V. M. ;Ka 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 1 views

Prenatal diagnosis of Canavan disease

✍ Reuben Matalon; Kimberlee Michals-Matalon 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 2 views

Prenatal diagnosis of Menkes disease

✍ Stephen G. Kaler; Zeynep Tümer 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 42 KB 👁 2 views

About 90-95 per cent of the patients have a severe clinical course leading to death in early childhood. ATP7A mutations associated with MD show great variety, from cytogenetic abnormalities to partial gene deletions to single base-pair changes. As a lethal X-linked trait, an estimated one-third of n

Prenatal diagnosis and management of con

Prenatal diagnosis and management of congenital heart defect: Significance of associated fetal anomalies and prenatal chromosome studies

✍ Wladimiroff, J. W. ;Stewart, P. A. ;Sachs, E. S. ;Niermeijer, M. F. ;Opitz, John 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB 👁 2 views