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Prenatal diagnosis by 3D ultrasound and MRI of an unusual malformation of cortical development with brain-in-brain appearance

✍ Scribed by Luca Valsecchi; Paolo Cavoretto; Lara Di Piazza; Maddalena Smid; Silvia Pontesilli; Roberta Scotti; Daniele Spagnolo; Cristina Baldoli


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
266 KB
Volume
37
Category
Article
ISSN
0091-2751

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✦ Synopsis


Abstract

A 31‐year‐old pregnant woman was referred for isolated mild ventriculomegaly and failure to visualize the left lateral ventricle's anterior horn on second trimester sonography (US). Three‐dimensional US suspected a frontal lesion deviating the midline. MRI revealed a mass compressing the ventricle. Follow‐up MRI described a “brain‐in‐brain” malformation: infolded microgyric cortex and white matter in frontal lobe extending to frontal horn and midline, irrorated by hypertophic Heubner artery. Conservative approach was chosen. Neurodevelopment at 1 year is normal. © 2009 Wiley Periodicals, Inc. J Clin Ultrasound, 2009