Prenatal Diagnosis and Genetic Counseling for Mosaic Trisomy 13
โ Scribed by Chih-Ping Chen
- Book ID
- 117697419
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 167 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1028-4559
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๐ SIMILAR VOLUMES
While the clinical features associated with full trisomy 13 have been well characterized, the clinical outcome associated with mosaic trisomy 13 is much less clear. The medical literature reports a broad range of possible clinical outcomes from severe mental retardation and birth defects to normal i
We describe six cases of trisomy 13 mosaicism detected at prenatal diagnosis. Most level I and level II trisomy 13 mosaicism detected at prenatal diagnosis is pseudomosaicism or confined placental mosaicism. Rarely, low-level mosaicism at chorionic villus sampling or amniocentesis reflects a true fe