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Premature ageing of the immune system underlies immunodeficiency in ataxia telangiectasia

✍ Scribed by Andrew Robert Exley; Samantha Buckenham; Elizabeth Hodges; Robert Hallam; Phil Byrd; James Last; Claire Trinder; Susan Harris; Nicholas Screaton; Anthony P. Williams; A. Malcolm R. Taylor; John M. Shneerson

Book ID
113541972
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
577 KB
Volume
140
Category
Article
ISSN
1090-2341

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Premature aging of the immune system in
Premature aging of the immune system in children with juvenile idiopathic arthritis
✍ Martina Prelog; Nora Schwarzenbrunner; Michaela Sailer-HΓΆck; Hannelore Kern; And πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 108 KB πŸ‘ 2 views

## Abstract ## Objective Juvenile idiopathic arthritis (JIA) is an autoimmune disease of the young. The pathogenesis is not completely understood. Premature aging, associated thymic involution, and compensatory autoproliferation could play important roles in the pathogenesis of autoimmunity. We un