Preliminary validation of an activation assay for ex vivo activated T cells utilized in cancer immunotherapy

Validation of an automated method of end

Validation of an automated method of endotoxin testing for use in the end-product testing of ex vivo activated T-lymphocytes used in a somatic cell therapy

✍ Zorina Pitkin; Prakash Chhugani; Aaron Chenette; Yuan-Jin Shen; Gary C. du Mouli 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 683 KB

The aim of this study was to compare two methods of endotoxin testing to optimize qualitycontrol testing methodologies required for the rapid and precise determination of pyrogenicity in cell or tissue products used in cellular therapies. An automated kinetic-chromogenic method for determination of