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Preliminary Studies on the Central Effects of Lorazepam, a New Benzodiazepine

โœ Scribed by HEDGES, ANNMARIE (author);TURNER, P. (author);HARRY, T. V. A. (author)


Book ID
127155801
Publisher
Wiley
Year
1971
Tongue
English
Weight
305 KB
Volume
11
Category
Article
ISSN
0021-9754

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Recovery from lorazepam tolerance and th
โœ Sandra E. File ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 516 KB

After 3 days of dosing rats with lorazepam (0.25 mg/kg), tolerance developed to its sedative effects. Recovery from this tolerance was rapid. No differences could be detected in undrugged behaviour 24 h after the last dose and no differences in response to a probe injection could be found when 2 dru