In a previous study a partial inhibition of viral replication was observed in HBeAg-positive patients after acyclovir (ACV) treatment. To assess those results and to evaluate different treatment regimens, a randomized controlled trial with ACV given at 45 mg/kg/day by continuous infusion (in 5 pati
Preliminary studies of acyclovir in chronic hepatitis B
β Scribed by Coleman I. Smith; George H. Scullard; Peter B. Gregory; William S. Robinson; Thomas C. Merigan
- Book ID
- 115678896
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 444 KB
- Volume
- 73
- Category
- Article
- ISSN
- 1555-7162
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π SIMILAR VOLUMES
Five patients with chronic non-A, non-B hepatitis were entered into a pilot therapeutic study of the antiviral agent acyclovir [9-(2-hydroxyethoxymethyl) guanine]. Each patient received acyclovir by slow intravenous infusion in a dosage of 5 mg/kg every 8 hr for 10 days. During therapy, serum aminot
A randomised, controlled trial comparing acyclovir, 45 mg/kg/day as a continuous IV infusion for 28 days, with no other therapy, was carried out in 30 stable HBsAg carriers seropositive for HBeAg for more than 6 months. Twenty-eight had hepatitis B virus DNA-polymerase activity and/or hepatitis B vi