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Preliminary results from a phase II trial evaluating 13 cis-retinoic acid with or without alpha tocopherol or observation in patients at high risk for lung cancer

✍ Scribed by Kelly, K; Dempsey, E; Kennedy, T; Miller, Y; Franklin, W; Prindiville, S; Holte, J; Bunn, P.A

Book ID
118570333
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
108 KB
Volume
29
Category
Article
ISSN
0169-5002

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✍ Sophie D. Fosså; Gerald H. J. Mickisch; Pieter H. M. De Mulder; Simon Horenblas; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB

## Background: In patients with metastatic renal cell carcinoma (mrcc), interferon-alpha (ifn) monotherapy leads to response rates of 5-15%, dependent on the selection of patients. in 1995, preclinical and clinical data indicated an improvement of these results if ifn was combined with 13-cis retin