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Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite

✍ Scribed by Cousty-Berlin, D.; Bergaud, B.; Bruyant, M.C.; Battmann, T.; Branche, C.; Philibert, D.


Book ID
122735200
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
698 KB
Volume
51
Category
Article
ISSN
0960-0760

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Metabolic disposition of pyrazinamide in
✍ L. W. Whitehouse; B. A. Lodge; A. W. By; B. H. Thomas πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 573 KB

Only limited studies have been reported on the disposition and pharmacokinetics of pyrazinamide (PZA) in both animals and humans. The metabolism of PZA has never been completely elucidated, consequently the metabolites of PZA, pyrazinoic acid (PA), 5-hydroxypyrazinoic acid (SHOPA), and 5-hydroxypyra