The pharmacokinetics and haemodynamic ef
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D. L. Wolf; A. E. Hearron; C. M. Metzler; J. J. Ferry; M. O. Froeschke; J. R. Lu
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Article
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1993
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Springer
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English
โ 636 KB
We have studied the pharmacokinetics and haemodynamic effects of nicorandil after a 12-h infusion. Nicorandil is a mixed vasodilator combining the actions of a nitrate and a potassium channel opener. Nicorandil was infused for 12 h in 21 healthy volunteers at rates of 0.05, 0.10, and 0.20 microgram.