Preliminary experience with chemotherapy in advanced salivary gland neoplasms
β Scribed by Belani, Chandra P. ;Eisenberger, Mario A. ;Gray, William C.
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 390 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0098-1532
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β¦ Synopsis
Eight patients with advanced incurable salivary gland carcinoma were treated with the combination of cyclophosphamide, doxorubicin, and cisplatin (CAP). There were three clinical complete responses and two excellent partial responses. One of the three nonresponders had symptomatic improvement without any response in the measurable dis-ease sites. Side effects were acceptable. All patients had moderate nausea and some degree of vomiting, which were adequately controlled by antiemetics. These results are preliminary but when considered with other reported trials using the same combination suggest an active treatment program for advanced neoplasms of the salivary glands.
π SIMILAR VOLUMES
## Abstract ## Background Epithelial neoplasms of salivary gland origin are relatively uncommon in children and adolescents. Over a 44βyear period, there were 38 cases affecting children under 19 years of age in our Pediatric HospitalβBased Tumor Registry. ## Procedure Medical charts of 38 patie