๐”– Bobbio Scriptorium
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Preliminary evaluation of177Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy

โœ Scribed by Lei Jiang; Zheng Miao; Richard H. Kimura; Hongguang Liu; Jennifer R. Cochran; Cathy S. Culter; Ande Bao; Peiyong Li; Zhen Cheng


Book ID
105964306
Publisher
Springer
Year
2010
Tongue
English
Weight
465 KB
Volume
38
Category
Article
ISSN
0340-6997

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Integrin __ฮฑ__~ฮฝ~__ฮฒ__~3~ is a receptor and is highly expressed on activated and proliferating endothelial cells during the growth and metastasis of solid tumors but not on resting endothelial cells and normal organs. Because RGD peptide binds to integrin __ฮฑ__~ฮฝ~__ฮฒ__~3~ receptor, a variety of radi