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Preirradiation of host (monkey) cells mitigates the effects of UV upon simian virus 40 DNA replication

โœ Scribed by A. Scaria; H.J. Edenberg

Book ID
116108158
Publisher
Elsevier Science
Year
1987
Weight
533 KB
Volume
183
Category
Article
ISSN
0167-8817

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Timing of ultraviolet light induced muta
Timing of ultraviolet light induced mutagenesis in simian virus 40 relative to viral DNA replication in monkey cells
โœ Cornelis, Jan J. ;Rommelaere, Jean ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Springer ๐ŸŒ English โš– 539 KB

Simian virus 40 (SV40) was used to probe ultraviolet light (UV)-induced mutation in mammalian cells. Viral mutations were scored as reversions of early and late temperature-sensitive (ts) mutants to the wild-type (WT) phenotype. When virus was exposed to moderate or high UV doses, WT revertants were