Preimplantation genetic diagnosis of β-thalassaemia
✍ Scribed by N El-Hashemite; D Wells; JDA Delhanty
- Book ID
- 118551916
- Publisher
- The Lancet
- Year
- 1996
- Tongue
- English
- Weight
- 25 KB
- Volume
- 348
- Category
- Article
- ISSN
- 0140-6736
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Preimplantation genetic diagnosis (PGD) allows the selection of unaffected IVF embryos for transfer in couples that are at risk for transmitting genetic diseases. For monogenic diseases, polymerase chain reaction (PCR)-based diagnosis is usually performed on single blastomeres. In Greece, up to 10 p
Preimplantation genetic diagnosis (PGD) offers couples at risk for transmitting an inherited disorder the possibility to avoid the need to terminate affected pregnancies, since it allows the selection of unaffected IVF embryos for transfer. PGD for monogenic diseases is most commonly accomplished by