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Preimplantation Genetic Diagnosis for Balanced Chromosome Translocation

✍ Scribed by K.P Xu; H.M Yuan; I Cholst; P Chung; O Davis; I Kligman; G Schattman; S Spandorfer; L.L Veeck; Z Rosenwaks

Book ID
119416439
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
30 KB
Volume
74
Category
Article
ISSN
1556-5653

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Preimplantation genetic diagnosis (PGD) offers polymerase chain reaction tests for an increasing range of single gene defects, and fluorescence in situ hybridization tests for sex determination (for X-linked conditions) and for aneuploidy detection. Patients carrying chromosome translocations with a