✦ LIBER ✦

Pregnane X Receptor: Promiscuous regulator of detoxification pathways

✍ Scribed by Marko Matic; Andre Mahns; Maria Tsoli; Anthony Corradin; Patsie Polly; Graham R. Robertson

Book ID: 116307277
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 492 KB
Volume: 39
Category: Article
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2006.08.017

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

M1802 Rifaximin is a Human Pregnane X Re

M1802 Rifaximin is a Human Pregnane X Receptor Activator in Human Colon Epithelial Cells and Regulate Detoxification Pathway

✍ Mencarelli, Andrea; Migliorati, Marco; Distrutti, Eleonora; Palladino, Giuseppe; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 47 KB

Epigenetic regulation of pregnane X rece

Epigenetic regulation of pregnane X receptor activity

✍ Tian, Yanan 📂 Article 📅 2013 🏛 Informa plc 🌐 English ⚖ 245 KB

Pregnane-X-receptor mediates the anti-in

Pregnane-X-receptor mediates the anti-inflammatory activities of rifaximin on detoxification pathways in intestinal epithelial cells

✍ Andrea Mencarelli; Marco Migliorati; Miriam Barbanti; Sabrina Cipriani; Giuseppe 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 629 KB

Transcriptional Regulation of the Human

Transcriptional Regulation of the Human Pregnane-X Receptor

✍ Gordon Gibson, G.; Phillips, Anna; Aouabdi, Sihem; Plant, Kate; Plant, Nick 📂 Article 📅 2006 🏛 Informa plc 🌐 English ⚖ 218 KB

The Nuclear Pregnane X Receptor: A Key R

The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism

✍ Kliewer, S. A. 📂 Article 📅 2002 🏛 Endocrine Society 🌐 English ⚖ 452 KB

Dual role of orphan nuclear receptor pre

Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice

✍ Simrat P. S. Saini; Ying Mu; Haibiao Gong; David Toma; Hirdesh Uppal; Songrong R 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 322 KB

The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are implicated in xenobiotic and endobiotic detoxification, including the clearance of toxic bilirubin. Previous studies have suggested both overlapping and preferential regulation of target genes by these receptors, but th