## Abstract Five new pregnane glycosides, perisepiumosides A–E (**1**–**5**, resp.), along with the seven known constituents **6**–**12**, were isolated from the root barks of __Periploca sepium__ Bge. (Asclepiadaceae), a traditional Chinese medicine used for the treatment of rheumatoid arthritis a
Pregnane glycosides from an antitumour fraction of Periploca sepium
✍ Scribed by Hideji itokawa; Junping Xu; Koichi Takeya
- Book ID
- 107842741
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 513 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0031-9422
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## Abstract A new cardenolide and two new pregnane glycosides, periplogenin 3‐[__O__‐__β__‐glucopyranosyl‐(1→4)‐__β__‐sarmentopyranoside] (**1**), (3__β__,20__S__)‐pregn‐5‐ene‐3,17,20‐triol 20‐[__O__‐__β__‐glucopyranosyl‐(1→6)‐__O__‐glucopyranosyl‐(1→4)‐__β__‐canaropyranoside] (**2**), and (3__β__,
## Abstract A new polyoxygenated pregnane genin and a new diphenylmethane, along with five known pregnane derivatives, were isolated from the root barks of __Periploca sepium.__ The structures of the new compounds were elucidated as (3__β__,14__β__)‐3,14‐dihydroxy‐21‐methoxypregn‐5‐en‐20‐one (**1**