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Pregnancy influences the plasma pharmacokinetics but not the cerebrospinal fluid pharmacokinetics of raltegravir: A preclinical investigation

โœ Scribed by Mahat, Mahamad Yunnus A.; Thippeswamy, B.S.; Khan, Farhin R.; Edunuri, Ramya; Nidhyanandan, Saranya; Chaudhary, Shilpee


Book ID
127196443
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
813 KB
Volume
65
Category
Article
ISSN
0928-0987

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โœ Slevin, M. L. ;Piall, E. M. ;Aherne, G. W. ;Johnston, A. ;Lister, T. A. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 638 KB

Subcutaneous bolus administration of cytosine arabinoside (Ara-C) has been used as an alternative to continuous intravenous infusion. However, the pharmacokinetics of subcutaneous bolus Ara-C have not been satisfactorily documented in man. The plasma concentrations of Ara-C were therefore compared f