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Pregnancy-associated plasma protein-A and insulin-like growth factor binding protein mRNAs in granulosa cells of dominant and subordinate follicles of preovulatory cattle

โœ Scribed by Consuelo A. Santiago; Justin L. Voge; Pauline Y. Aad; Dustin T. Allen; Dan R. Stein; Jerry R. Malayer; Leon J. Spicer


Book ID
116410707
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
138 KB
Volume
28
Category
Article
ISSN
0739-7240

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Pregnancy-associated plasma protein-A (P
โœ Kimberly R. Kalli; Bing-Kun Chen; Laurie K. Bale; Erica Gernand; Michael T. Over ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 632 KB

## Abstract Pregnancyโ€Associated Plasma Proteinโ€A (PAPPโ€A) proteolyses insulinโ€like growth factor binding proteinโ€4 (IGFBPโ€4), thereby regulating local IGF availability. Reduced PAPPโ€A mRNA expression has been reported in ovarian cancer specimens compared to normal ovarian surface epithelial cells