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Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat

✍ Scribed by Serena Stopponi; Lorenzo Somaini; Andrea Cippitelli; Giordano de Guglielmo; Marsida Kallupi; Nazzareno Cannella; Gilberto Gerra; Maurizio Massi; Roberto Ciccocioppo

Publisher
Springer
Year
2011
Tongue
English
Weight
237 KB
Volume
220
Category
Article
ISSN
0033-3158

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## Abstract Previous studies showed that cytosolic and microsomal fractions from rat ventral prostate are able to biotransform ethanol to acetaldehyde and 1‐hydroxyethyl radicals via xanthine oxidase and a non P450 dependent pathway respectively. Sprague Dawley male rats were fed with a Lieber and