Content: Accelerating the course of preliminary-preformulation through prediction of molecular physical properties and integrated analytical data management / Robert S. DeWitte, Michel Hachey, and Harry G. Brittain --
Prediction of crystallographic characteristics / Steve Spanton --
Salt selection for pharmaceutical compounds / Sherif I. Badawy, Miriam K. Franchini, and Munir A. Hussain --
Intelligent preformulation design and predictions using artificial neural networks / Nkere K. Ebube --
Developing a profile of the active pharmaceutical ingredient / Harry G. Brittain --
Particle morphology and characterization in preformulation / Alan Rawle --
Preparation and identification of polymorphs and solvatomorphs / Harry G. Brittain --
X-ray diffraction methods for the characterization of solid pharmaceutical materials / Jean Blachere and Harry G. Brittain --
Spectroscopic methods for the characterization of drug substances / Harry G. Brittain --
Thermal analysis and calorimetric methods for the characterization of new crystal forms / Dennette Murphy Shelley Rabel --
Solubility methods for the characterization of new crystal forms / Harry G. Brittain --
Overview of the solid dosage form preformulation program / Harry G. Brittain --
Drug-excipient interactions appropriate to solid dosage forms / Moji Christianah Adeyeye --
Methods for the determination of the physical and chemical stability of a new solid dosage form / Harry G. Brittain --
Dissolution testing / Chuck Collins and George Wong --
Structure, content, and format of the preformulation report / Ram N. Gidwani --
Significance of drug substance physicochemical properties in regulatory quality by design / Sau Lawrence Lee, Andre S. Raw, and Lawrence Yu.