Preformed antibodies to biliary epithelial cells and acute rejection of liver allografts
β Scribed by Jean Gugenheim
- Book ID
- 116650259
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 79 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0168-8278
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Loss of bile duct epithelium is characteristic of early chronic rejection following liver transplantation. Recent studies have suggested that intrahepatic biliary epithelial cells can transform into myofibroblasts. This study examines the induction and molecular regulation of this transition during
Liver sinusoidal endothelial cells (LSECs) may be implicated in the induction of liver allograft rejections. We studied the clinical consequences of LSEC-reactive antibodies and their functional capacity in modulating T-cell responses during acute rejections. Pre-and posttransplant sera and T lympho