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Preferred phosphodiester conformations in nucleic acids. A virtual bond torsion potential to estimate lone-pair interactions in a phosphodiester

✍ Scribed by A. R. Srinivasan; N. Yathindra; V. S. R. Rao; S. Prakash


Publisher
Wiley (John Wiley & Sons)
Year
1980
Tongue
English
Weight
371 KB
Volume
19
Category
Article
ISSN
0006-3525

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✦ Synopsis


Abstract

The lone‐pair orbital interactions arising in a phosphodiester are incorporated into semiempirical conformational energy calculations using a unifold “torsional potential” around the virtual bond linking the ester oxygen atoms. The results explain the observed experimental data better than other methods.