## Abstract Gene amplification is one of the mechanisms to activate oncogenes in many cancers, including esophageal adenocarcinoma (EA). In the present study, we used twoβdimensional restriction landmark genome scanning to clone a __Not__I/__Dpn__II fragment that showed increased genomic dosage in
β¦ LIBER β¦
Preferred location for the development of esophageal adenocarcinoma within a segment of intestinal metaplasia
β Scribed by J. Theisen; H. J. Stein; M. Feith; W. K. H. Kauer; H. J. Dittler; D. Pirchi; J. R. Siewert
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 370 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0930-2794
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From 1940 to 1963, 1,884 patients with adenocarcinomas of the large intestine (including colon and rectum) were seen at the University of Minnesota Medical Center. Patients with lesions of the rectum comprised 53.2% of the group and numbered 1,002, including 693 (36.8%) with cancers of the rectal am